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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIP4K2B
All Species:
24.55
Human Site:
S58
Identified Species:
49.09
UniProt:
P78356
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78356
NP_003550.1
416
47378
S58
N
H
T
I
N
E
L
S
N
V
P
V
P
V
M
Chimpanzee
Pan troglodytes
XP_001172818
377
42820
S58
N
H
T
I
N
E
L
S
N
V
P
V
P
V
M
Rhesus Macaque
Macaca mulatta
XP_001099389
382
43672
E58
D
N
H
L
F
N
K
E
N
M
P
S
H
F
K
Dog
Lupus familis
XP_548154
416
47327
S58
N
H
T
I
N
E
L
S
N
V
P
V
P
V
M
Cat
Felis silvestris
Mouse
Mus musculus
Q80XI4
416
47300
S58
N
H
T
I
N
E
L
S
N
V
P
V
P
V
M
Rat
Rattus norvegicus
O88377
416
47245
S58
N
H
T
I
N
E
L
S
N
V
P
V
P
V
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510625
479
54696
S122
D
R
R
I
N
E
L
S
H
V
Q
I
P
V
M
Chicken
Gallus gallus
Q5F356
405
46073
P57
E
L
S
H
V
Q
I
P
V
M
L
M
P
D
D
Frog
Xenopus laevis
Q5PQ01
419
47633
I66
N
H
S
V
N
E
L
I
Q
V
P
V
P
V
M
Zebra Danio
Brachydanio rerio
Q6IQE1
416
47361
N58
N
H
S
I
N
D
L
N
Q
V
P
V
P
V
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392797
416
47916
V57
L
S
H
V
N
I
P
V
V
L
L
P
D
D
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RY89
769
87385
T364
R
Y
T
V
G
K
I
T
P
V
P
P
R
E
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.5
69.4
99.2
N.A.
99
98.3
N.A.
62
77.6
67.7
65.3
N.A.
N.A.
58.6
N.A.
N.A.
Protein Similarity:
100
89.4
80
99.7
N.A.
99.7
99
N.A.
73
88.9
82
80.5
N.A.
N.A.
74
N.A.
N.A.
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
60
6.6
73.3
73.3
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
100
40
100
N.A.
100
100
N.A.
80
40
86.6
93.3
N.A.
N.A.
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
0
0
0
0
9
0
0
0
0
0
0
9
17
9
% D
% Glu:
9
0
0
0
0
59
0
9
0
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
9
% F
% Gly:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
59
17
9
0
0
0
0
9
0
0
0
9
0
0
% H
% Ile:
0
0
0
59
0
9
17
9
0
0
0
9
0
0
0
% I
% Lys:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
9
% K
% Leu:
9
9
0
9
0
0
67
0
0
9
17
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
17
0
9
0
0
67
% M
% Asn:
59
9
0
0
75
9
0
9
50
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
9
9
9
0
75
17
75
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
17
0
9
0
0
0
0
% Q
% Arg:
9
9
9
0
0
0
0
0
0
0
0
0
9
0
0
% R
% Ser:
0
9
25
0
0
0
0
50
0
0
0
9
0
0
0
% S
% Thr:
0
0
50
0
0
0
0
9
0
0
0
0
0
0
0
% T
% Val:
0
0
0
25
9
0
0
9
17
75
0
59
0
67
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _